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1, 25-dihydroxy vitamin D3 ameliorated lupus nephritis in an animal model

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eMediNexus    26 July 2022

  • Lupus nephritis is a common and severe complication of systemic lupus erythematosus.
  • Its aetiology and pathology, however, remain unknown to date.
  • 1,25-dihydroxy vitamin D3 is the active form of vitamin D, which has shown important functions in inflammatory and immune-related diseases.

Reference: Li X, Liu J, Zhao Y, xu N, et al. 1, 25-dihydroxyvitamin D3 ameliorates lupus nephritis through inhibiting the NF-κB and MAPK signalling pathways in MRL/Ipr mice. BMC Nephrology. 2022; 23, Article number 243. 

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